Phytochemical analysis, antioxidative activity, cytotoxicity, and antimicrobial activity of two Vietnamese Camellia species: Camellia quephongensis and Camellia puhoatensis

Ninh The Son, Nguyen Thi An Giang, Nguyen Thi To Trang, Le Thi Huong, Dao Thi Minh Chau, Vu Van Khoa, Nguyen Ngoc Hoa, Nguyen Quang Hop, Do Ngoc Dai
Author affiliations

Authors

  • Ninh The Son Institute of Chemistry, Vietnam Academy Science and Technology, 18 Hoang Quoc Viet, Nghia Do, Ha Noi, Viet Nam https://orcid.org/0000-0002-2413-7496
  • Nguyen Thi An Giang Faculty of Biology, College of Education, Vinh University, 182 Le Duan, Vinh, Nghe An, Viet Nam https://orcid.org/0000-0003-3243-1422
  • Nguyen Thi To Trang Faculty of Biology, College of Education, Vinh University, 182 Le Duan, Vinh, Nghe An, Viet Nam
  • Le Thi Huong Faculty of Biology, College of Education, Vinh University, 182 Le Duan, Vinh, Nghe An, Viet Nam
  • Dao Thi Minh Chau Faculty of Biology, College of Education, Vinh University, 182 Le Duan, Vinh, Nghe An, Viet Nam
  • Vu Van Khoa Department of Orthopedic and Outpatient Treatment, Vietduc University Hospital, 40 Trang Thi, Hoan Kiem, Ha Noi, Viet Nam
  • Nguyen Ngoc Hoa Nghean General Friendship Hospital, Km5, Lenin Boulevard, Vinh, Nghe An, Viet Nam https://orcid.org/0000-0003-2585-7257
  • Nguyen Quang Hop https://orcid.org/0000-0001-9689-4448
  • Do Ngoc Dai Faculty of Agriculture, Forestry and Fishery, Nghe An University of Economics, 51 Ly Tu Trong, Vinh, Nghe An, Viet Nam https://orcid.org/0000-0002-7741-9454

DOI:

https://doi.org/10.15625/2525-2518/18107

Keywords:

Camellia quephongensis, Camellia puhoatensis, antioxidative, cytotoxic, antimicrobial

Abstract

Camellia quephongensis and C. puhoatensis are two Vietnamese perennial plants, which has engaged the attention due to their great values in beverage and pharmacology. For the first time, the phytochemical and biological evaluations of the ethanol extracts from the flowers and leaves of two Vietnamese Camellia species C. puhoatensis and C. quephongensis were carried out. Phytochemical screenings determined the appearance of flavonoids, tannins, saponins, free-reducing sugars, and polysaccharides. These ethanol extracts are promising antioxidants since they showed strong or better than the standard trolox in lipid peroxidation inhibition activity. These alcohol extracts were also superior to the positive control streptomycin in antimicrobial assays against the growth of Gram-positive bacterium Enterococcus faecalis ATCC299212 and Gram-negative bacteria Pseudomonas aeruginosa ATCC27853 and Salmonella enterica ATCC13076. In another approach, these extracts exhibited cytotoxicity towards seven cancer cell lines A549, HT-29, SK-Mel-2, HepG2, MCF-7, Hela, and MKN-7 at different levels of results. It needs to get more studies, focusing on the explanations by mechanism of actions

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Published

29-08-2025

How to Cite

[1]
S. Ninh The, “Phytochemical analysis, antioxidative activity, cytotoxicity, and antimicrobial activity of two Vietnamese Camellia species: Camellia quephongensis and Camellia puhoatensis”, Vietnam J. Sci. Technol., vol. 63, no. 4, pp. 679–689, Aug. 2025.

Issue

Vol. 63 No. 4 (2025)

Section

Natural Products

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